Chinese Journal of Tissue Engineering Research ›› 2013, Vol. 17 ›› Issue (34): 6215-6220.doi: 10.3969/j.issn.2095-4344.2013.34.023

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Nd-YAG laser damage affects the optical properties of intraocular lens

Liu Li1, Li Ai-jun2, Wang Shuo1, Wang Ying1   

  1. 1Medical Device Testing Center, National Institute for Food and Drug Control, Beijing 100050, China; 2Key Laboratory of Vision Loss and Restoration of Ministry of Education, Eye Center of Peking University, Department of Ophthalmology of Peking University Third Hospital, Beijing 100191, China
  • Online:2013-08-20 Published:2013-08-20
  • Contact: Li Ai-jun, M.D., Attending physician, Assistant researcher, Key Laboratory of Vision Loss and Restoration of Ministry of Education, Eye Center of Peking University, Department of Ophthalmology of Peking University Third Hospital, Beijing 100191, China laj100@sina.com
  • About author:Liu Li, Master, Assistant researcher, Medical Device Testing Center, National Institute for Food and Drug Control, Beijing 100050, China liuli_7823@163.com
  • Supported by:

    General Project of National Natural Science Foundation of China, No. 81170877*; National Key Basic Research and Development Planning Project, No. 2011CB510200*; Youth Development Project of National Institute for Food and Drug Control, No. 2012B9*

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Abstract:

BACKGROUND: Posterior capsulotomy with Nd-YAG laser is the main method in clinic for the treatment of after-cataract, but it often damages the intraocular lens during the treatment.

OBJECTIVE: To research the effect of Nd-YAG laser damage on the intraocular lens optical properties based on the laboratory testing.

METHODS: Ten hydrophobic acrylic intraocular lenses were collected as the test samples, and then Nd-YAG laser with the pulse energy of 5.0 mJ was used for 50 single-pulse laser shooting on the center of a circle with the diameter of 3 mm on the back surface of each sample. The shapes of the damaged area on the samples were observed under scanning electron microscope after laser shooting. Optical analyzer was used to test the average optical power and optical power distribution.

RESUTLS AND CONCLUSION: The intraocular lenses were observed under scanning electron microscope under 40 times and 1 000 times enlargement and showed that there was circle-like depression with the diameter about 50 μm on the back surface of the intraocular lenses, and there was protruding around the depression. Intraocular lens optical analyzer test results showed that there was no significant change in the average optical power of intraocular lenses after laser damage, but the optical power distribution was changed significantly. In the center of the circle with the diameter of 3 mm, the optical power showed annular distribution radiating to the surrounding tissue with the center of circle-like depression area. The Nd-YAG laser damage has less effect on the optical power, but has great effect on the optical power distribution of intraocular lenses.

Key words: biomaterials, biomaterial academic discussion, intraocular lens, lens opacities, after-cataract, Nd-YAG laser, optical power, imaging quality, lens posterior capsulotomy, crystal damage, optical power distribution, National Natural Science Foundation of China

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